Fare Guide

Estimated lowest fares found within 7 days

Cheapest Airline KLM
Cheapest Month June
Cheapest Day of the Week Wednesday
Cheapest Airline KLM

The cheapest airline(s) flying from Panama City to Madrid is KLM.

  • KLM KLM
  • Air France Air France
  • Avianca Avianca
  • Air Europa Air Europa
  • Iberia Iberia
  • Turkish Airlines Turkish Airlines
  • American Airlines American Airlines
  • United Airlines United Airlines
  • Aeromexico Aeromexico
  • Emirates Emirates
Cheapest Month June

Travel Period: May 2025 - April 2026

The cheapest month(s) to fly from Panama City to Madrid is June.

  • May 2025
  • Jun 2025
  • Jul 2025
  • Aug 2025
  • Sep 2025
  • Oct 2025
  • Nov 2025
  • Dec 2025
  • Jan 2026
  • Feb 2026
  • Mar 2026
  • Apr 2026
Cheapest Day of the Week Wednesday

The cheapest day(s) of the week to fly from Panama City to Madrid is Wednesday.

  • Sun Sunday
  • Mon Monday
  • Tue Tuesday
  • Wed Wednesday
  • Thu Thursday
  • Fri Friday
  • Sat Saturday

Flight Schedules

Last Updated: Wed, 2 Apr, 2025

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  • Availability
    • M
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  • 20:25 PTY
    13:15 MAD
    9Hrs, 50m Direct
  • PTYPanama City Tocumen International Airport 20:25 - MAD 13:15 9h 50m Direct
  • PTYPanama City Tocumen International Airport 20:25
  • MADMadrid Barajas Airport 13:15
  • 9h 50m
  • Direct
  • Air Europa (UX 56)Boeing 787 9
  • Air Europa (UX 56)
    • M
    • -
    • -
    • -
    • F
    • S
    • -
  • Boeing 787 9
  • 20:25 PTY
    13:15 MAD
    9Hrs, 50m Direct
  • PTYPanama City Tocumen International Airport 20:25 - MAD 13:15 9h 50m Direct
  • PTYPanama City Tocumen International Airport 20:25
  • MADMadrid Barajas Airport 13:15
  • 9h 50m
  • Direct
  • Air Europa (UX 56)Boeing 787 8
  • Air Europa (UX 56)
    • -
    • T
    • W
    • -
    • -
    • -
    • S
  • Boeing 787 8
  • 17:35 PTY
    10:25 MAD
    9Hrs, 50m Direct
  • PTYPanama City Tocumen International Airport 17:35 - MAD 10:25 9h 50m Direct
  • PTYPanama City Tocumen International Airport 17:35
  • MADMadrid Barajas Airport 10:25
  • 9h 50m
  • Direct
  • Iberia (IB 258)Airbus
  • Iberia (IB 258)
    • M
    • -
    • -
    • T
    • -
    • S
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  • Airbus
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What’s the fastest flight time from Panama City to Madrid?

The fastest flight time for direct flights from Panama City to Madrid is 9 hours 50 minutes. Check latest flight schedules & prices on Wego.

What’s the most popular airline flying from Panama City to Madrid?

The most popular airline flying from Panama City to Madrid is Air Europa. Find the latest flight deals on Wego.

How far is Madrid from Panama City?

The flight distance between Panama City and Madrid is 8163km. Check all available flights on Wego.

When is the earliest and latest flight of the day?

The earliest flight of the day departs at 17:35. The last flight of the day departs at 20:25. See the full list of flight times on Wego.

How many airlines offer direct flights from Panama City to Madrid?

There are 2 airlines that offer direct flights from Panama City to Madrid. Find out the list of airlines on Wego.